Gene ML1740c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML1740c
Gene length939 bp
IdentifierML1740c
Location 2099988 bp
Protein summary information
Molecular mass33949.0 Da
Isoelectric point9.91
Protein length313 amino acids
Structural information
PFAMPF00106
Orthologs
M. tuberculosis H37RvRv3057c
M. lepromatosis Mx1-22AMLPM_1740
Cross-references
UniProtQ9CBP7
Gene OntologyMetabolic process, Oxidoreductase activity, Binding
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE
CommentsML1740c, len: 312 aa. Probable oxidoreductase, probably short-chain alcohol dehydrogenase/reductase (EC 1.1.-.-). Similar to several including: Thermotoga maritima 3-oxoacyl-[acyl-carrier protein] reductase SW:FABG_THEMA (Q9X248) (246 aa), Fasta scores: E(): 1.4e-18, 33.2% identity in 193 aa overlap and Mycobacterium tuberculosis possible ketoacyl reductase Rv3057c TR:P95101 (EMBL:Z83866) (287 aa), Fasta scores: E(): 0, 81.8% identity in 280 aa overlap. Contains Pfam match to entry PF00106 adh_short, short chain dehydrogenase. Contains PS00061 Short-chain dehydrogenases/reductases family signature.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS20999882100926-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1740c|ML1740c
MVKTAQYFVGKRCFVTGAASGIGRATALRLAAYGAELYLTDRHCDGLAQTVSEARALGAQVPEYRALDISDYDEVAAFGADIHARHPSMDIVMNIAGVSVWGTVDRLTHDQWSNVVAINLMGPIHIIETFVPAILAAGRGGHLVNVSSAAGLVALPWHAAYSASKYGLRGLSEVLRFDLARYRIGVSVVVPGAVRTPLVDTIEIAGVDRQDPRFSRWVDRFRGHAVSAERAAEKILAGVAKNRYLIYTSHDIRVLYGFKRLAWWPYGVVMKQVNVVFTRALRPSPATMRCVEPIKVGVYSQPRSGEGGKSGN
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