Gene ML1752c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML1752c
Gene length909 bp
IdentifierML1752c
Location 2121326 bp
Protein summary information
Molecular mass33328.9 Da
Isoelectric point6.17
Protein length303 amino acids
Structural information
PFAMPF00563
Orthologs
M. tuberculosis H37RvRv1357c
M. lepromatosis Mx1-22AMLPM_1752
Cross-references
UniProtQ9CBP4
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
Productconserved hypothetical protein
CommentsML1752c, len: 302 aa. Conserved hypothetical protein. Similar to many including the C-terminus of several putative phosphodiesterases e.g. Streptomyces coelicolor TR:Q9Z584 (EMBL:AL035569) (746 aa), Fasta scores: E(): 2.5e-32, 38.4% identity in 305 aa overlap as well as several proteins of undefined function e.g. Mycobacterium tuberculosis Rv1357c SW:YD57_MYCTU (Q11027) (307 aa), Fasta scores: E(): 0, 73.9% identity in 261 aa overlap. Also similar to the C-terminus of ML1750 from M. leprae. Contains Pfam match to entry PF00563 DUF2, Domain of unknown function 2.
Functional categoryConserved hypotheticals
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS21213262122234-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1752c|ML1752c
LPIEGAMRSSSLPDGCSDRSADSRGSGEVKDRSSGWFYGHHDREQRSVHDGLLQVIPAALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPARFISLAERNGMIVPLTTFVIEQACRHIRNWRDDSTNPRPFVSVNVSARNIRDPSFLSMVERVLGETGLPAHALRLELTENASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNLPVDMVKLAGEFIENLGGDIRGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDFGCDAAQGWHFAKALPADFFTE
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