Gene ML1768 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameuspA
Gene length987 bp
IdentifierML1768
Location 2143283 bp
Protein summary information
Molecular mass36228.5 Da
Isoelectric point9.83
Protein length329 amino acids
Structural information
PFAMPF00528
Orthologs
M. tuberculosis H37RvRv2316
M. lepromatosis Mx1-22AMLPM_1768
Cross-references
UniProtQ9CBN8
Gene OntologyIntegral to membrane, Plasma membrane, Sugar:hydrogen symporter activity, Carbohydrate transport
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE SUGAR-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER USPA
CommentsML1768, len: 328 aa. Probable sugar transport integral membrane protein. Similar to M. tuberculosis Rv2316 TR:P71896 (EMBL:Z79702) (290 aa), Fasta scores: E(): 0, 82.4% identity in 289 aa overlap probable sugar transport protein uspA, and to many others e.g. Thermococcus litoralis maltore transporter malF TR:O51924 (EMBL:AF012836) (300 aa), Fasta scores: E(): 4.7e-28, 33.6% identity in 283 aa overlap. Also similar to ML1426, ML1087, ML1425 and ML1088 from M. leprae. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS21432832144269+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1768|uspA
MCAHFNTSMTNTGDDTEQSDEVGSISRLRGRKTHRTRALTKNHPRSIALAYALLAPSLFGVVTFLLLPIIVVIWLSLFRWDLLGPLHYVGLANWRSVLTDPNFANSLIVTAVFVAIVVPTQTMLGLLIATMLARQLPGTGVFRTLYVLPWICAPLAIAVLWRWLLAPTDGAFSMVLRHRIEWLSDPSLALPVVSAVVVWTNVGYVSLSFLAGLLSIPEDINAAARTDGADAWQRFWRITLPMLRPTMFFVLVTGIVSTAQVFDTVYALTDGGPKSRTDLVAHRIYAEAFGSAAIGRASVMAVLLFVVLFGVTVVQHLYFQRRISYELT
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