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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE SUGAR-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER USPB
CommentsML1769, len: 274 aa. Probable uspB, sugar-transport integral membrane protein ABC transporter. Similar to M. tuberculosis Rv2317 TR:P71895 (EMBL:Z79702) uspB, sugar-transport integral membrane protein ABC transporter (274 aa), Fasta scores: E(): 0, 85.0% identity in 274 aa overlap, and to many others e.g. Thermomonospora fusca cellobiose transport permease bglB TR:AAF37729 (EMBL:AF086819) (305 aa), Fasta scores: E(): 1.9e-24, 30.2% identity in 275 aa overlap. Also similar to ML1425 and ML1088 from M. leprae. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component. Note previously known as uspE.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS21442562145080+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML1769|uspB
MSSPSRLSNAVTYAGLTLGALITVAPFALGLLTSFTSAHQFTTGTPLQLPRPPTLANYAGLSGAGFLRATAVTALMTAVILLGQLTFSVLAGYAFARLRFPGRDTLFWAYIMTLMVPATVTVVPMYMMMAQVGLRNTFWALVLPFMFGSPYAIFLLREHFRIIPNDLINAARLDGANTLDVIVHVVIPSNRSVLAALTLITVVSQWNNFMWPLVITSGNKWRVLTVATADLQSRFNAQWTLVMAATTVAIVPLIVLFVGFQRHIIPSIVVSGLK
      
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