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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE LIPASE/ESTERASE LIPG
CommentsML1899, len: 304 aa. probable lipG, lipase/esterase (EC 3.1.-.-). Similar to M. tuberculosis putative hydrolase Rv0646c TR:P96935 (EMBL:Z92772) (301 aa), Fasta scores: E(): 0, 71.3% identity in 303 aa overlap, and to others e.g. Escherichia coli macrolide 2'-phosphotransferase II TR:P77026 (EMBL:D85892) (279 aa), Fasta scores: E(): 1.3e-15, 31.3% identity in 291 aa overlap, and Streptomyces peucetius 10-carbomethoxy-13-deoxycarminomycin esterase TR:Q54809 (EMBL:L40425) (298 aa), Fasta scores: E(): 1e-09, 28.6% identity in 301 aa overlap. Also similar to ML0862 from M. leprae. Contains Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS22836412284555+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML1899|lipG
VEVRSGYATSGDLKLYYEDMGNVDDPPVLLIMGLGAQLVLWRTAFCEKLVAQGLRVVRYDNRDVGLSSRTDSTEQPCPSQPLTARLIRFWLGQRNACAYTLEDMTDDAVALLDHLSIERAHIVGASMGGMIAQIFAARFPTRTRSLAVFFSSNNRPFLPPPAPRALLALLTGPPTGSRRDVVVDNVVRVTKITGSPLYRMPEEQVRTNAAEIYDRSFYPLGVSRQFSAILGSGSLLHYNQRIIAPTVVIHGRADKLVRPSSGRAVARAITGARLVLFDGMGHDLPQQLWDQAVGVLMSNFAKAS
      
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