Gene ML1919c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML1919c
Gene length642 bp
IdentifierML1919c
Location 2302772 bp
Protein summary information
Molecular mass22565.6 Da
Isoelectric point6.02
Protein length214 amino acids
Structural information
PFAMPF00484
Orthologues
M. tuberculosisRv3588c
Cross-references
UniProtQ9CBJ1
Gene OntologyCarbonate dehydratase activity, Zinc ion binding, Carbon utilization
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductCARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE)
CommentsML1919c, len: 213 aa. Probable carbonic anhydrase (EC 4.2.1.1). Similar to M. tuberculosis putative carbonic anhydrase Rv3588c TR:O53573 (EMBL:AL022075) (207 aa), Fasta scores: E(): 0, 84.5% identity in 207 aa overlap, and to others e.g. Chlamydomonas reinhardtii carbonic anhydrase precursor TR:Q39589 (EMBL:U41189) (267 aa), Fasta scores: E(): 7.9e-19, 34.4% identity in 192 aa overlap. Contains Pfam match to entry PF00484 Pro_CA, Prokaryotic-type carbonic anhydrases. Contains PS00704 Prokaryotic-type carbonic anhydrases signature 1. Contains PS00705 Prokaryotic-type carbonic anhydrases signature 2.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS23027722303413-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1919c|ML1919c
MFNTNPIAAWKALKEGNERFVAGQPAHPSQSVEHRASLADTQKPLAVIFGCADSRVAAELVFDQGLGDMFVVRTVGHVIDSAVLGSIEYAVTVLDVPLVVVLGHDSCGAVTAALAAINEGNLPSGYVRDVVERVAPSVLLGRRDGLTRVDEFEERHVHETVAQAMARSTAIAQRVAAGTLAIVGVTYHLADGRAVLRTHIGNLGEEVQLSHCS
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