Gene ML1920 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namemutY
Gene length894 bp
IdentifierML1920
Location 2303412 bp
Protein summary information
Molecular mass32410.0 Da
Isoelectric point9.05
Protein length298 amino acids
Structural information
PFAMPF00730, PF10576
Orthologues
M. tuberculosisRv3589
Cross-references
UniProtQ9CBJ0
Gene OntologyBase-excision repair, Endonuclease activity, 4 iron, 4 sulfur cluster binding
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE ADENINE GLYCOSYLASE MUTY
CommentsML1920, len: 297 aa. Probable mutY, DNA glycosylase (EC 3.2.2.-). Similar to M. tuberculosis probable DNA glycosylase Rv3589 TR:O53574 (EMBL:AL022075) (304 aa), Fasta scores: E(): 0, 74.9% identity in 303 aa overlap, and to many others e.g. Escherichia coli A/G-specific adenine glycosylase mutY SW:MUTY_ECOLI (P17802) (350 aa), Fasta scores: E(): 1.8e-21, 33.2% identity in 244 aa overlap. Also similar to ML2301 from M. leprae. Contains Pfam match to entry PF00730 Endonuclease_3, Endonuclease III.
Functional categoryInformation pathways
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS23034122304305+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1920|mutY
MAHIVPQIKISTGGLLDWYRQSCRDLPWRQPGVTAWQILVSEFMLQQTPVARVLSIWPDWVQRWPTPSTTAAASAADVLRAWGKLGYPRRAKRLHESATIIAREHDDVVPDDVDVLLTMPGIGSYTARAVACFAYHQPVPVVDTNVRRVVARAVHGRADAGPPSATRDHADVSSLLPGKKAAPQFSMALMELGAIVCTARSPRCGLCPLNECAWRHAGYPPAQGPARRAQQYAGTDRQVRGLLLDVLRAKDSPVTGTELNVTWLTNSIQLDRALDSLLADGLVTRTTDGRFALTGEG
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