Gene ML1925c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namesodC
Gene length723 bp
IdentifierML1925c
Location 2310778 bp
Protein summary information
Molecular mass24087.1 Da
Isoelectric point6.94
Protein length241 amino acids
Structural information
PFAMPF00080
Orthologs
M. tuberculosis H37RvRv0432
M. lepromatosis Mx1-22AMLPM_1925
Cross-references
UniProtQ9CBI6
Gene OntologyCopper ion binding, Oxidation-reduction process, Plasma membrane, Superoxide dismutase activity, Superoxide metabolic process, Zinc ion binding, Antioxidant activity
Enzyme Classification1.15.1.1
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE PERIPLASMIC SUPEROXIDE DISMUTASE [CU-ZN] SODC
CommentsML1925c, len: 240 aa. Probable periplasmic superoxide dismutase precursor (EC 1.15.1.1). Similar to M. tuberculosis superoxide dismutase precursor (Cu-Zn) Rv0432 TR:P96278 (EMBL:Z84724) (240 aa), Fasta scores: E(): 0, 72.0% identity in 239 aa overlap, and weakly similar to many others e.g. Photobacterium leiognathi superoxide dismutase SW:SODC_PHOLE (P00446) (173 aa), Fasta scores: E(): 0.0018, 29.6% identity in 189 aa overlap. Contains Pfam match to entry PF00080 sodcu, Copper/zinc superoxide dismutase (SODC). Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
Functional categoryVirulence, detoxification, adaptation
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS23107782311500-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1925c|sodC
MSKLAGHRNVAAVTRSALSLSFVAACVALLSACIQNQPPATLPGTTPTVWTGSPAPSGMLGAEAESMGPPNIITRLNAPDGTQVATAKFEFNNGFATITIATTGVGHLAPGFHGVHIHKVGKCEPSSAGPTGGAPGDFLSAGGHFQVPGHTVEPASGNLTSLQVRKDGIGTLVTTTDAFTMNDLLAGQKTAIIIHAGADNFGNIPPERYSQVNGTPGPDATTISTGDAGKRVACGVIGAD
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