Gene ML1950c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML1950c
Gene length876 bp
IdentifierML1950c
Location 2336696 bp
Protein summary information
Molecular mass31377.5 Da
Isoelectric point6.79
Protein length292 amino acids
Structural information
PFAMPF01522
Orthologs
M. tuberculosis H37RvRv1096
M. lepromatosis Mx1-22AMLPM_1950
Cross-references
UniProtQ7AQ13
Gene OntologyHydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, Carbohydrate metabolic process
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE GLYCOSYL HYDROLASE
CommentsML1950c, len: 291 aa. Possible glycosyl hydrolase (EC 3.-.-.-), possibly deacetylase or esterase. Similar to M. tuberculosis Rv1096 TR:O53444 (EMBL:AL021897) glycosyl hydrolase (291 aa), Fasta scores: E(): 0, 81.3% identity in 289 aa overlap, and to Streptomyces lividans acetylxylan esterase precursor TR:Q54413 (EMBL:M64552) (335 aa), Fasta scores: E(): 2.8e-18, 31.8% identity in 236 aa overlap. Also similar to ML2649 from M. leprae. Contains Pfam match to entry PF01522 Polysac_deacet, Polysaccharide deacetylase.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS23366962337571-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1950c|ML1950c
VLKRPDTQAWRYSRTVFGVVAAGAVLVIGALTGHVTRADDMSCAQVKCIALTFDDGPGPYTDRLVQILKDNDAKATFFLIGNKVATNPAGAKRIVDAGMEIGSHTWEHPNMTMLSTEDIADQFSRANHAITVATGRTPTLWRPAGGLSNEAVRQVAGRYGQAEILWDVIPFDWTNDSDTVATRCMLMMQIKPGSVVLFHDTYSSTVDLVYQFIPVLKANGYRLVTVTELLGPRAPGSSYGRRENGPPVNQLHDIPANLIPALPNTSSPKPMPNFPITDISGQNSGGSNDGA
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