Gene ML2046 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namelldD2
Gene length1245 bp
IdentifierML2046
Location 2435566 bp
Protein summary information
Molecular mass45337.2 Da
Isoelectric point8.01
Protein length415 amino acids
Structural information
PFAMPF01070
Orthologs
M. tuberculosis H37RvRv1872c
M. lepromatosis Mx1-22AMLPM_2046
Cross-references
UniProtQ9CBF2
Gene OntologyElectron carrier activity, Metabolic process, Oxidoreductase activity, Fmn binding
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE L-LACTATE DEHYDROGENASE (CYTOCHROME) LLDD2
CommentsML2046, len: 414 aa. Possible lldD2, L-lactate dehydrogenase (EC 1.1.2.3). Similar to Mycobacterium tuberculosis LLDD2 TR:P95143 (EMBL:AQ102036) fasta scores: E(): 0, 85.0% in 413 aa, and to Escherichia coli L-lactate dehydrogenase SW:LLDD_ECOLI (P33232) fasta scores: E(): 0, 37.3% in 383 aa. Contains Pfam match to entry PF01070 FMN_dh, FMN-dependent dehydrogenase. Contains PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS24355662436810+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2046|lldD2
MAAKRRMPRVHDLAPLIQFKRPKFGATKRRLEAALTIQDLRCIAKQRTPKAAFDYTDGAAEDELSIKRAQQAFRDIEFHPAILRDVTNVCAGWDVLGHSVLLPFGIAPTGFTRLMHTEGEIAGARAAAAAGIPFSLSTLATSAIEDVVAAVPQGRKWFQLYMWRDRDRSMALVERAADAGYDALLVTVDVPVAGARLRDTRNGMSIPPALTLRTVFDALPHPRWWIDLLTTEPLAFASLDRWSGTVSDYLNTMFDPSVTFDDLAWIKTQWPGKFVVKGIQTLDDARAVVERGIDGVVLSNHGGRQLDRAPVPFHLLPTVAREFGKDTEILLDTGIMSGADIVAAIALGARCTLVGRAYLYGLMAGGEAGVRRAIEILESGVIRTMQLLGVTCLEELSPRHVTQLQRLGPIEPPA
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