Gene ML2077c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namegcvH
Gene length399 bp
IdentifierML2077c
Location 2469475 bp
Protein summary information
Molecular mass14038.4 Da
Isoelectric point4.06
Protein length133 amino acids
Structural information
PFAMPF01597
Orthologs
M. tuberculosis H37RvRv1826
M. lepromatosis Mx1-22AMLPM_2077
Cross-references
UniProtO32920
Gene OntologyGlycine decarboxylation via glycine cleavage system, Lipoic acid binding, Glycine cleavage complex
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE GLYCINE CLEAVAGE SYSTEM H PROTEIN GCVH
CommentsML2077c, len: 132 aa. Probable gcvH, glycine cleavage system H protein. Similar to Mycobacterium tuberculosis probable glycine cleavage system H protein SW:GCSH_MYCTU (Q50607) fasta scores: E(): 0, 78.4% in 134 aa, and to Escherichia coli glycine cleavage system H protein SW:GCSH_ECOLI (P23884) fasta scores: E(): 1.5e-22, 49.6% in 129 aa. Contains Pfam match to entry PF01597 GCV_H, Glycine cleavage H-protein. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS24694752469873-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2077c|gcvH
VSDIPSDLHYTAEHEWIRRSREDTVRVGLTDFAQSTLGDVVFVQLPEVGAELAAGKSFGEVESTKSVSDLYAPVSGTVSAVNTDLEGSPQLVNSDPYGAGWLLDVHVSDVGALESAIATLLDAETYRGTLTK
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