Gene ML2131c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namepdxH
Gene length621 bp
IdentifierML2131c
Location 2533165 bp
Protein summary information
Molecular mass22991.7 Da
Isoelectric point4.66
Protein length207 amino acids
Structural information
PFAMPF01243, PF10590
Orthologs
M. tuberculosis H37RvRv2607
M. lepromatosis Mx1-22AMLPM_2131
Cross-references
UniProtO33065
Gene OntologyOxidation-reduction process, Pyridoxamine-phosphate oxidase activity, Pyridoxine biosynthetic process, Fmn binding
Enzyme Classification1.4.3.5
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE PYRIDOXAMINE 5'-PHOSPHATE OXIDASE PDXH (PNP/PMP OXIDASE) (PYRIDOXINEPHOSPHATE OXIDASE) (PNPOX) (PYRIDOXINE 5'-PHOSPHATE OXIDASE)
CommentsML2131c, len: 206 aa. Probable pdxH, pyridoxamine 5'-phosphate oxidase (EC 1.4.3.5). Similar to Mycobacterium tuberculosis pyridoxamine 5'-phosphate oxidase Rv2607 SW:PDXH_MYCTU (O06207) fasta scores: E(): 0, 69.3% in 205 aa, and to Escherichia coli pyridoxamine 5'-phosphate oxidase SW:PDXH_ECOLI (P28225) fasta scores: E(): 9.8e-27, 43.3% in 171 aa. Contains Pfam match to entry PF01243 Pyridox_oxidase, Pyridoxamine 5'-phosphate oxidase. Contains PS01064 Pyridoxamine 5'-phosphate oxidase signature.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS25331652533785-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2131c|pdxH
VEYGSVEKDGSPDLDTDWLYDGWLTLFCKWIDDAERAGVAEPNAMVLATVANGRPVSRSVLCKGADEAGIIFFTNYDSDKGDDLAATPYASVTFPWYQLGRQVHIRGPVSTVDPQVSEDYWSKRPRGSQLGAWASHQSRPIASRTALLDQLLEVTVRFADSELIPLPPNWGGYLIVPEVVEFWQGRENRVHNRIRVTGGCIERLQP
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