Gene ML2140c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML2140c
Gene length432 bp
IdentifierML2140c
Location 2541992 bp
Protein summary information
Molecular mass15771.1 Da
Isoelectric point9.5
Protein length144 amino acids
Structural information
PFAMPF01047
Orthologs
M. tuberculosis H37RvRv0880
M. lepromatosis Mx1-22AMLPM_2140
Cross-references
UniProtO33060
Gene OntologyRegulation of transcription, dna-dependent, GO:0006350, Sequence-specific dna binding transcription factor activity, Intracellular
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY MARR-FAMILY)
CommentsML2140c, len: 143 aa. Possible transcriptional regulator, MarR family. Similar to Mycobacterium tuberculosis transcriptional regulator protein Rv0880 SW:Y880_MYCTU (Q10542) fasta scores: E(): 0, 90.2% in 143 aa, and to Streptomyces coelicolor putative marR-family protein TR:CAB93410 (EMBL:AL357524) fasta scores: E(): 1.6e-13, 39.6% in 134 aa. Also similar to ML2696 and ML0550 from M. leprae. Contains Pfam match to entry PF01047 MarR, MarR family.
Functional categoryRegulatory proteins
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS25419922542423-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2140c|ML2140c
MLDSDARLASDLSLAVMRLARQLRFRNPQSPVSLSQLSALTTLANEGAMTPGALAIRERVRPPSMTRVIASLADMGFVDREPHPVDGRQVLVSVSQSGAELVKAARRARQEWLVERLMTLNSDKRDILRNAADLILELIDESP
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