Gene ML2174 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namecdd
Gene length405 bp
IdentifierML2174
Location 2586148 bp
Protein summary information
Molecular mass14251.2 Da
Isoelectric point4.72
Protein length135 amino acids
Structural information
PFAMPF00383
Orthologs
M. tuberculosis H37RvRv3315c
M. lepromatosis Mx1-22AMLPM_2174
Cross-references
UniProtQ9CBD3
Gene OntologyCytidine metabolic process, Zinc ion binding, Cytidine deaminase activity
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE CYTIDINE DEAMINASE CDD (CYTIDINE AMINOHYDROLASE) (CYTIDINE NUCLEOSIDE DEAMINASE)
CommentsML2174, len: 134 aa. Probable cdd, cytidine deaminase (EC 3.5.4.5). Similar to Mycobacterium tuberculosis cytidine deaminase Rv3315c TR:O53367 (EMBL:AL021841) fasta scores: E(): 3e-28, 56.8% in 132 aa, and to Mus musculus cytidine deaminase SW:CDD_MOUSE (P56389) fasta scores: E(): 5.2e-12, 39.8% in 118 aa. Contains Pfam match to entry PF00383 dCMP_cyt_deam, Cytidine and deoxycytidylate deaminase zinc-binding region. Contains PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS25861482586552+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2174|cdd
MGDVNWDTLQKAAVAARANSYAPYSNFPVGVAGFVNDGRLITGVNVENASYGLALCAECSMISALYATGGGRLVAVYCVDGNGDSLMPCGRCRQLLYEHGGPELKIMTPKGVQTMAQLLPQAFNPQERIFGNDE
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