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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE THIOSULFATE SULFURTRANSFERASE CYSA2 (RHODANESE-LIKE PROTEIN) (THIOSULFATE CYANIDE TRANSSULFURASE) (THIOSULFATE THIOTRANSFERASE)
CommentsML2198, len: 277 aa. Probable cysA2, thiosulfate sulfurtransferase (EC 2.8.1.1). Similar to several e.g. Mycobacterium tuberculosis putative thiosulfate sulfurtransferase SW:THTR_MYCTU (O05793) Rv0815c and Rv3117 fasta scores: E(): 0, 85.2% in 277 aa, and to Saccharopolyspora erythraea putative thiosulfate sulfurtransferase SW:THTR_SACER (P16385) fasta scores: E(): 0, 74.1% in 274 aa, and to Corynebacterium glutamicum thiosulfate sulfurtransferase SW:THTR_CORGL (P71121) fasta scores: E(): 0, 44.5% in 218 aa. Also similar to ML0728 from M. leprae. Contains 2 Pfam matches to entry PF00581 Rhodanese, Rhodanese-like domain. Contains PS00683 Rhodanese C-terminal signature.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS26120682612901+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML2198|cysA2
MARSDVLVSADWAESNLDSANIVFVEVDEDTSTYDGDHIAGAIKLDWRADLQDPIKRDFIDTQQFSKLLGDRGISNDNTVILYGGNNNWFAAYAYWYFKLYRHDKVKLLDGGRKKWELDGRPLSTDTVTRPATSYAAAAPDNTIRAFRDEVIASIKIKNLVDVRSPDEFSGKLLAPAHLPQEQSQRPGHIPSAINIPWSKAANEDGTFKSDEQLAKLYADAGLDRLKETIVYCRIGERSSHTWFVLRELLGYQNVKNYDGSWTEYGSLVGVPIELGS
      
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