Gene ML2226c (ptrBa, ptrBb)
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) |
| Comments | ML2226c, len: 724 aa. Probable ptrB, protease II (EC 3.4.21.83). Similar at the C-terminal region to Mycobacterium tuberculosis hypothetical ptrBb Rv0782 OR MTCY369.26 TR:P71835 (EMBL:Z80226) fasta scores: E(): 0, 77.8% identity in 519 aa, and at the N-terminal region to Rv0781|ptrBa (236 aa), fasta scores: E(): 4.1e-62, (69.912% identity in 226 aa overlap). Also similar to Escherichia coli protease ii PTRB OR TLP SW:PTRB_ECOLI (P24555; P78068) fasta scores: E(): 0, 38.2% identity in 702 aa. Contains Pfam match to entry PF00326 Peptidase_S9, Prolyl oligopeptidase family. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2642867 | 2645041 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML2226c|ptrB
MTKTSRGTPVPPIAKRVETRRERHGDVFFDPYEWLRDNNNPEVVAYLDAENDYVNQMTAHLEPLQQKIFNEIKARTKENDLSVPTRQANWWYYSRTFEGKQYRVQCRCPVASPDDWTPPALYENTEISGEQVLLDSNAEAEGHAFFALGTFMVSLDSNLLAYSVDFVGDERYTLRFKDLRTGERYPDEIVGIGAGATWAADNRTVYYLTLDESRRPDTVWRCRLGSGQPSEQVYHEADERFWLAVGLSRSEAYIFIAAGSAITSEWRYADSTNPDAQFTVVLPRRDGIEYSVEHAPSGLVGGQDRFLILHNDGAVNFTLVESPVSNPEQQRTLIPHRDDVRLDSADAFAGYLVVSYRREALPRVQLWPIDPDGSYGEPEEISFESELMWVSLEANSNWVSPKLRIRAGSFVTPVRVYDVDLATGERTLLREQPVLGGYKHEDYVERREWAQADDGTWIPVSIVHRAAIRFPAPAVLYGYGAYEICVDPSFSIPRLSLLDRGMMFVIAHVRGGGEMGRLWYEHGKLLEKKNTFTDFISVAKHLVDSGQTRSQELVALGGSAGGLLMGVVANIAPDLFTGILAQVPFVDPLTTMLDPSLPLTVTEWDEWGNPLIDSDFYSYIKSYSPYENVEAKQYPAILAMTSLHDTRVHYVEPAKWIAALRHTKSDGNPVLLKTQMAAGHAGISGRYKAWQETAFQYAWLLAAVDVDQYGTATEVDDLGGGAQG
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