Gene ML2227c
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PHOSPHORIBOSYLAMINOIMIDAZOLE- SUCCINOCARBOXAMIDE SYNTHASE PURC (SAICAR SYNTHETASE) |
| Comments | ML2227c, len: 297 aa. purC, phosphoribosylaminoimidazole-succinocarboxamid synthase (EC 6.3.2.6). Similar to Mycobacterium tuberculosis phosphoribosylaminoimidazole-succinocarboxamide synthase PURC OR Rv0780 OR MTCY369.24 SW:PUR7_MYCTU (Q59566; P77904) fasta scores: E(): 0, 81.5% identity in 297 aa, and to Haemophilus influenzae putative phosphoribosylaminoimidazole-succinocarboxamide synthase PURC OR HI1726 SW:PUR7_HAEIN (P43851) fasta scores: E(): 0, 46.0% identity in 287 aa, and to Candida maltosa phosphoribosylamidoimidazole-succinocarboxamide synthase ADE1 SW:PUR7_CANMA (P27602) fasta scores: E(): 0, 45.1% identity in 288 aa. Contains Pfam match to entry PF01259 SAICAR_synt, SAICAR synthetase. Contains PS01057 SAICAR synthetase signature 1. Contains PS01058 SAICAR synthetase signature 2. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2645038 | 2645931 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML2227c|purC
MRPALFDYRHLASGKVREIYRIDDEHLLMVASDRISAFDYVLDSTIPDKGRILTAMSVFFFSFVDAPNHLAGPPDDPRIPEEVLGRALVVRQLDMLPMECVARGYLTGSGLLDYQATGKVCGIPLPPGLVEASRFAAPLFTPAMKAVLGEHDENISFSRMIEMVGVVRANQLRDRTLQIYLQAADHALKTGIIIADTKFEFGIDRDGNLLLADEIFTPDSSRYWSVDDYRVGVVQRSFDKQFVRNWLVSPESGWVRAGALSPPSLPDDIIEATRLCYVEVYERISGMSFDDWIGPGA
Bibliography
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