Gene ML2273
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE UBIQUINONE/MENAQUINONE BIOSYNTHESIS METHYLTRANSFERASE MENH (2-heptaprenyl-1,4-naphthoquinone methyltransferase) |
| Comments | ML2273, len: 238 aa. Probable menH, ubiquinone/menaquinone biosynthesis methyltransferase (EC 2.1.1.-). Similar to Mycobacterium tuberculosis putative ubiquinone/menaquinone biosynthesis methyltransferase Rv0558 or MTCY25D10.37 TR:O06424 (EMBL:Z95558) (234 aa) fasta scores: E(): 0, 83.3% identity in 228 aa. Similar to many e.g. Streptomyces coelicolor putative ubiquinone/menaquinone methyltransferase SC10A7.27C TR:Q9XAP8 (EMBL:AL078618) (231 aa) fasta scores: E(): 0, 64.9% identity in 225 aa and to Escherichia coli ubiquinone/menaquinone biosynthesis methyltransferase UbiE ubiE SW:UBIE_ECOLI (P27851) (251 aa) fasta scores: E(): 2.7e-19, 42.8% identity in 229 aa. Contains Pfam match to entry PF01209 Ubie_methyltran, ubiE/COQ5 methyltransferase family. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2697290 | 2698006 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML2273|menH
LPPGSVDVVSRAALDKDPRDVVAMFDDVAHRYDLTNTVLSLGQDRYWRRATRSALRIGPGQKVLDLAAGTAVSTAELSKSGAWCVAADFSVRMLATGGARKVPKVAADATQLPFSDGVFDAVTISFGLRNIADYQAALREMARVTRPGGQLVVCEFSTPTNALVANVYTEYLMRALPQVARLVSSNPDAYIYLAESIRAWPDQVTLACQLSRTGWASPRWRNLTGGIVALHAADKPVR
Bibliography
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