Gene ML2300c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML2300c
Gene length648 bp
IdentifierML2300c
Location 2725032 bp
Protein summary information
Molecular mass22496.9 Da
Isoelectric point6.76
Protein length216 amino acids
Structural information
PFAMPF08534
Orthologs
M. tuberculosis H37RvRv3673c
M. lepromatosis Mx1-22AMLPM_2300
Cross-references
UniProtQ9CB93
Gene OntologyOxidoreductase activity, Cell redox homeostasis
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE MEMBRANE-ANCHORED THIOREDOXIN-LIKE PROTEIN (THIOL-DISULFIDE INTERCHANGE RELATED PROTEIN)
CommentsML2300c, len: 215 aa. Possible membrane protein, thioredoxin-like protein (thiol-disulfide interchange protein). Similar to Mycobacterium tuberculosis Rv3673c or MTV025.021C TR:O69641 (EMBL:AL022121) membrane protein, thioredoxin-like protein (227 aa) fasta scores: E(): 0, 71.2% identity in 215 aa. Shows weak similarity to Bacillus subtilis ResA protein resA SW:RESA_BACSU (P35160) (181 aa) fasta scores: E(): 5e-06, 31.6% identity in 114 aa and to thioredoxins. Contains hydrophobic, possible membrane-spanning region. Contains PS00194 Thioredoxin family active site.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS27250322725679-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2300c|ML2300c
MKTLTPKTCGTIVVLAVVVALVAALVGQLRDNARTIEMTQATIEREHRDADTPAALAGPREHANLPPCPDAGSGPGPAVLRGVVLECASDGFAVDVARALAGRRVVLNLWASWCASCLGELPAMVEYQRRVGSDVMVVTVHQDENEMAALLRLAQLGVRLPTLQDGRRRVAAAFGVANVIPTTVVLRPDGSVAQTLPRALVSVDQIAAAVGNDTG
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