Gene ML2314c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameglpK
Gene length1527 bp
IdentifierML2314c
Location 2741820 bp
Protein summary information
Molecular mass54640.3 Da
Isoelectric point4.62
Protein length509 amino acids
Structural information
PFAMPF00370, PF02782
Orthologs
M. tuberculosis H37RvRv3696c
M. lepromatosis Mx1-22AMLPM_2314
Cross-references
UniProtQ9CB81
Gene OntologyCarbohydrate metabolic process, Glycerol kinase activity, Glycerol-3-phosphate metabolic process, Atp binding
Enzyme Classification2.7.1.30
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE GLYCEROL KINASE GLPK (ATP:GLYCEROL 3-PHOSPHOTRANSFERASE)(GLYCEROKINASE) (GK)
CommentsML2314c, len: 508 aa. Probable glpK, glycerol kinase (EC 2.7.1.30). Similar to Mycobacterium tuberculosis glycerol kinase Rv3696c SW:GLPK_MYCTU (O69664) (517 aa) fasta scores: E(): 0, 91.5% identity in 508 aa and Escherichia coli glycerol kinase SW:GLPK_ECOLI (P08859; Q59381) (501 aa) fasta scores: E(): 0, 51.4% id in 500 aa. Contains Pfam match to entry PF00370 FGGY, FGGY family of carbohydrate kinases. Contains PS00445 FGGY family of carbohydrate kinases signature 2. Contains PS00933 FGGY family of carbohydrate kinases signature 1.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS27418202743346-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2314c|glpK
LAEFAEFIAAIDQGTTSTRCVIFDHNGAEVARHQLEHEQILPRSGWVEHNPVEIWERTASVLMSVLNATNLSAKDIAALGITNQRETTLVWNRNTGRPYCNAIVWQDTRTDRIAVALDRDGRGEVIRRKAGLPPATYFSGGKLQWILENVDGVGAAAENGEALFGTPDTWLLWNLTGGPRGGVHVTDVTNASRTMLMDLEKLDWDDELLSFFSIPRAMLPAIASSSPLQPYGVTLADGPVGGEVPITGVLGDQHAAMVGQVCLDAGEAKNTYGTGNFLLLNTGEAIVRSGNGLLTTVCYQFGDAKPVYALEGSIAVTGSAVQWLRDQLGIISGAAQSESLARQVVDNGGVYFVPAFSGLFSPYWRSDARGAIVGLSRFNTNAHLARATLEAICYQSRDVVDAMAADSGVRLDVLKVDGGITSNDLCMQIQADVLGVDVVRSVVAETTALGSAYAAGLAVGFWAGPSDLRANWQEDKRWTPTWGEDQRAAAYAGWRKAVQRTLDWVDVS
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