Gene ML2326 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML2326
Gene length1236 bp
IdentifierML2326
Location 2757748 bp
Protein summary information
Molecular mass43725.7 Da
Isoelectric point8.83
Protein length412 amino acids
Structural information
PFAMPF08245, PF08353
Orthologues
M. tuberculosisRv3712
Cross-references
UniProtQ7APW6
Gene OntologyBiosynthetic process, Ligase activity, Atp binding
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
Productpossible ligase
CommentsML2326, len: 411 aa. Possible ligase (EC 6.-.-.-). Similar to several MurCDEF-family proteins e.g. Mycobacterium tuberculosis UDP-N-acetylmuramate--alanine ligase Rv2152c SW:MURC_MYCTU (O06225) (494 aa) fasta scores: E(): 0.0013, 25.6% identity in 387 aa. Also highly similar to Mycobacterium tuberculosis hypothetical 43.4 kDa protein Rv3712 TR:O69679 (EMBL:AL022121) (413 aa) fasta scores: E(): 0, 84.3% id in 413 aa. Contains Pfam match to entry PF01225 Mur_ligase, Mur ligase family.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS27577482758983+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2326|ML2326
VFTVRARLALAAGASARWTSRITGRGAGTMIGGLVAITLDRSILSQLGAGRRTIVVTGTNGKSTTTRMTVDALSTLAPGSVATNAEGANMDAGLVAALAANRAATLAVLEVDEMHVPRVADALTPHIVVLLNLSRDQLDRVGEINVIERTLRTGLARHPTAVVIANCDDVLMTSVAYDSPNVVWVAAGGTWSNDSVSCPRSGEVIVRKNRHWYSTGADFKRPSPHWWFDDNTLYGPDELALPMRLALPGSVNRGNAAQAVATAVMLGADATTAVAAVSKVDEVAGRYRSVRIGEHTTRILLAKNPAGWQEALSMVDTQAAGVVISINGQVPDGKDLSWLWDVRFEHFEKIPVVAAGERGTDLAVRLRYAGVEHTLVHDTVAAIASCPPGQVEVVANYTAFRQLQRRLARHG
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