Gene ML2334 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML2334
Gene length1263 bp
IdentifierML2334
Location 2764455 bp
Protein summary information
Molecular mass47091.3 Da
Isoelectric point6.92
Protein length421 amino acids
Structural information
PFAMPF02353
Orthologs
M. tuberculosis H37RvRv3720
M. lepromatosis Mx1-22AMLPM_2334
Cross-references
UniProtQ9CB74
Gene OntologyLipid biosynthetic process, Cyclopropane-fatty-acyl-phospholipid synthase activity
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE FATTY ACID SYNTHASE
CommentsML2334, len: 420 aa. Possible fatty acid synthase. Similar to Mycobacterium tuberculosis fatty acid synthase Rv3720 TR:O69687 (EMBL:AL022121) (420 aa) fasta scores: E(): 0, 86.4% identity in 420 aa. The C-terminus is similar to several proteins involved in cyclopropane-fatty-acyl-phospholipid synthesis e.g. Escherichia coli SW:CFA_ECOLI (P30010) (381 aa) fasta scores: E(): 1.3e-27, 34.5% identity in 278 aa. Contains PS00107 Protein kinases ATP-binding region signature.
Functional categoryLipid metabolism
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS27644552765717+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2334|ML2334
MAEILGILTATGQQPLKFTAYDGSTAGHDDAEIGLDLCSPRGATYLATAPGELGIARAYVAGDLQARGVHPGDPYTLLKTLTDRVQFKRPSLRVLASVVRSLGVEHLLPIAPPPQETPPRWRRITDGLLHSKTRDAEAIRHHYDVSNRFYEWVLGPSMTYTCAVYPNAEATLEEAQENKYRLIFEKLRLQPGDRLLDVGCGWGGMVRYAARRGVRVIGATLSAEQAKWARKAIDNEGLAEIAQVRYSDYRDIRETEFDAVSSIGLTEHIGVKNYPAYFNFLKLKLRTGGLLLNHCITRRDNKSTSFAGGFTDRYVFPDGELTGSGRITTEIQEVGLEVLHEENFRHHYAMTLRDWCHNLVEHWEDAVAEVGLPIAKVWGLYMAASRVAFEQNNLQLHHILATKVDVWGDNSLPTRPWWTP
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