Gene ML2428c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namegalE2
Gene length1095 bp
IdentifierML2428c
Location 2903588 bp
Protein summary information
Molecular mass39604.4 Da
Isoelectric point9.85
Protein length365 amino acids
Structural information
PFAMPF01370
Orthologs
M. tuberculosis H37RvRv0501
M. lepromatosis Mx1-22AMLPM_2428
Cross-references
UniProtQ9CB57
Gene OntologyCellular metabolic process, Coenzyme binding, Catalytic activity
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE UDP-GLUCOSE 4-EPIMERASE GALE2 (GALACTOWALDENASE) (UDP-GALACTOSE 4-EPIMERASE) (URIDINE DIPHOSPHATE GALACTOSE 4-EPIMERASE) (URIDINE DIPHOSPHO-GALACTOSE 4-EPIMERASE)
CommentsML2428c, len: 364 aa. Possible galE2, UDP-glucose 4-epimerase (EC 5.1.3.2). Similar to Mycobacterium tuberculosis UDP-glucose 4-epimerase Rv0501 SW:Y501_MYCTU (Q11166) (376 aa) fasta scores: E(): 0, 84.0% identity in 368 aa, and to Streptomyces violaceoruber dTDP-glucose dehydratase TR:Q56173 (EMBL:L37334) (321 aa) fasta scores: E(): 2.9e-07, 30.4% identity in 332 aa.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS29035882904682-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2428c|galE2
VDSSSGQDGGGTGGVVPYPKVVLVTGACRFLGGYLTARLAQNPLINAVIAVDAIAPSKDMLRRMGHAEFVRADIRNPFIAKVIRNGEVDTVVHADAASYAPRSCGSAALKELNVMGAMQLFAACQKAPTVRRVVLKSTSAVYGSGSRDPVMFTEDSSSWRSFREGFAKDSLDIEGYARGLGRRRSDIAVTILRLADMIGPAMDTTLSRYLAGPLVPTMCGRDARLQLLHEQDALGALECAAMTGKAGTFNIGASGIMMLSQAIRRAGRIAVPIPSFGVWALDLLRWVNRYTEITRDQFEYLSYGRVMDTTRMGSELGYHPKWTTAGAFDDYVRGRGLTPIIDLHRVRYFEGRAIALAQRWSSRN
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