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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductTWO COMPONENT SENSORY TRANSDUCTION PROTEIN REGX3 (TRANSCRIPTIONAL REGULATORY PROTEIN) (PROBABLY LUXR-FAMILY)
CommentsML2439c, len: 198 aa. regX3, response regulator protein (sensory transduction protein). Similar to Synechococcus sp alkaline phosphatase synthesis transcriptional regulatory protein SphR SW:SPHR_SYNP7 (P39663) (257 aa) fasta scores: E(): 6.6e-33, 47.1% identity in 206 aa, and to Mycobacterium tuberculosis sensory transduction protein RegX3 Rv0491 SW:RGX3_MYCTU (Q11156) (227 aa) fasta scores: E(): 0, 95.9% identity in 197 aa. Also similar to ML0773, ML0174 and ML2123 from M. leprae. Contains Pfam match to entry PF00486 trans_reg_C, Transcriptional regulatory protein, C terminal. Contains Pfam match to entry PF00072 response_reg, Response regulator receiver domain.
Functional categoryRegulatory proteins
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS29144972915093-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML2439c|regX3
VVTDGPAALAEFDRSGADIVLLDLMLPGMSGTDVYKQLRVRSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGGDDDSEISDGVLESGPLRMDVERHVVSVNGYAITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGVDYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLES
      
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