Gene ML2449 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML2449
Gene length816 bp
IdentifierML2449
Location 2924649 bp
Protein summary information
Molecular mass28178.9 Da
Isoelectric point4.75
Protein length272 amino acids
Structural information
PFAMPF00795
Orthologs
M. tuberculosis H37RvRv0480c
M. lepromatosis Mx1-22AMLPM_2449
Cross-references
UniProtQ9CB47
Gene OntologyNitrogen compound metabolic process, Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE AMIDOHYDROLASE
CommentsML2449, len: 271 aa. Possible amidohydrolase. Similar to several including: Mycobacterium tuberculosis amidohydrolase Rv0480c SW:Y480_MYCTU (Q11146) (280 aa), fasta scores: E(): 0, 81.9% identity in 270 aa, and to Streptomyces coelicolor putative hydrolase TR:Q9XA70 (EMBL:AL096822) fasta scores: E(): 1.5e-16, 34.9% identity in 272 aa. Contains Pfam match to entry PF00795 CN_hydrolase, Carbon-nitrogen hydrolase. Contains PS01227 Uncharacterized protein family UPF0012 signature.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS29246492925464+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2449|ML2449
MRIALAQILSGTDPVANLRLVREYTGQATDAGATLVVFPEATMCRFGVPLGPVAEPIDGPWANGVRQIATEAGITIIAGIFTPADDGRVMNTLIAAGPGTPNQPDTHYHKIHLYDAFGFTESRTVTAGHEPVVITVDDVQVGLTICYDIRFPALYTELARRGAQLIVVCASWGSGAGKLEQWTLLARARALDSMSYVAAVGQADPGGALTDSGPSSAAPTGVGGSLVASPLGEVVASAGTESKLVVADIDVDNVTTARENIAVLRNRSHFA
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