Gene ML2472c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nametyrA
Gene length984 bp
IdentifierML2472c
Location 2947166 bp
Protein summary information
Molecular mass33626.4 Da
Isoelectric point5.8
Protein length328 amino acids
Structural information
PFAMPF02153
Orthologs
M. tuberculosis H37RvRv3754
M. lepromatosis Mx1-22AMLPM_2472
Cross-references
UniProtQ9CB34
Gene OntologyPrephenate dehydrogenase (nadp+) activity, Tyrosine biosynthetic process, Binding
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPREPHENATE DEHYDROGENASE TYRA (PDH) (HYDROXYPHENYLPYRUVATE SYNTHASE)
CommentsML2472c, len: 327 aa. Probable tyrA, prephenate dehydrogenase (EC 1.3.1.12). Similar to Mycobacterium tuberculosis putative oxidoreductase Rv3754 TR:O69721 (EMBL:AL022121) fasta scores: E(): 0, 80.0% identity in 300 aa and to Bacillus subtilis prephenate dehydrogenase TyrA SW:TYRA_BACSU (P20692) fasta scores: E(): 1.6e-15, 29.1% identity in 285 aa. Contains Pfam match to entry PF02153 PDH, Prephenate dehydrogenase.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS29471662948149-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2472c|tyrA
VSILDGGWDCVGRPVCVLGLGLIGGSIMRATAEAGREVFGYNRSVKGAQSARSDGFDATTKLADALVRAADTHALIVLAVPMPALPAMLAHIRELAPNCPLTDVTSVKTAVLDAVVSVGLQARFVGGHPMTGTAQSGWGAGHGGLFNRTSWVLSVDDHVDPAVWSMVMTLALDCGALVLPAKSDEHDAAAAAISHMPHLLAEALAVAAAEVPLAFAVAAGSFRDATRVAGTAPDLVRAMCEGNSGQLLSSVDRVIELLCRARDSLACNNSVAELVEAGHAARARYDSFPRSDIVTVIIGAENWREDLAAAGRAGGVIRSALPSLGSP
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