Gene ML2507c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namedcd
Gene length573 bp
IdentifierML2507c
Location 2987957 bp
Protein summary information
Molecular mass20788.5 Da
Isoelectric point5.23
Protein length191 amino acids
Structural information
PFAMPF00692
Orthologs
M. tuberculosis H37RvRv0321
M. lepromatosis Mx1-22AMLPM_2507
Cross-references
UniProtQ9CB17
Gene OntologyDutp biosynthetic process, Pyrimidine ribonucleotide biosynthetic process, Dctp deaminase activity
Enzyme Classification3.5.4.13
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE DEOXYCYTIDINE TRIPHOSPHATE DEAMINASE DCD (DCTP DEAMINASE)
CommentsML2507c, len: 190 aa. Probable dcd, deoxycytidine triphosphate deaminase (EC 3.5.4.13). Similar to Mycobacterium tuberculosis deoxycytidine triphosphate deaminase Rv0321 SW:DCD_MYCTU (O07247) fasta scores: E(): 0, 89.5% identity in 190 aa and to Escherichia coli deoxycytidine triphosphate deaminase SW:DCD_ECOLI (P28248) fasta scores: E(): 7.5e-20, 42.6% identity in 188 aa. Contains Pfam match to entry PF00692 dUTPase, dUTPase. Contains PS00017 ATP/GTP-binding site motif A (P-loop).
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS29879572988529-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2507c|dcd
VLLSDRDLRAEITAGRFSIDPFDDTLVQPSSIDVRLDCMFRVFNNTRYTHIDPARQQDELTSLVELVDGEPFVLHPGGFVLGSTLELFTLPEDLAGRLEGKSSLGRLGLLTHSTAGFIDPGFCGHITLELSNVANLPITLWPGMKIGQLCVLRLTSPAEHPYGSASAGSKYQGQRGPTPSRSYENFIKNT
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