Gene ML2551 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameaac
Gene length549 bp
IdentifierML2551
Location 3039200 bp
Protein summary information
Molecular mass20168.8 Da
Isoelectric point7.07
Protein length183 amino acids
Structural information
PFAMPF00583
Orthologues
M. tuberculosisRv0262c
Cross-references
UniProtQ9CD24
Gene OntologyMetabolic process, N-acetyltransferase activity
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductAMINOGLYCOSIDE 2'-N-ACETYLTRANSFERASE AAC (AAC(2')-IC)
CommentsML2551, len: 182 aa. aac, aminoglycoside 2'-N-acetyltransferase (EC 2.3.1.-). Highly similar to several mycobacterial aminoglycoside-resistance determinants e.g. Mycobacterium tuberculosis aminoglycoside 2'-n-acetyltransferase Aac OR Rv0262c SW:AAC2_MYCTU (P95219; P72033) fasta scores: E(): 0, 78.7% identity in 178 aa.
Functional categoryVirulence, detoxification, adaptation
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS30392003039748+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2551|aac
MDTHHVHTARLVHTADLDGETLRRLQQMVTDAFAGDFDETDWEHALGGMHALIWRHGTIIAHAAVVQRRLFYHGNALRCGYLEGVAVRKDCRGRGLVHALLDAIEQVIRGAYQFGALSSSDRARRVYMSRGWLPWLGPTSVLAPTGVIRTPDDDGSVFVLPVGINPDTSSGLMCDWRAGNVW
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