Gene ML2568c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML2568c
Gene length627 bp
IdentifierML2568c
Location 3063270 bp
Protein summary information
Molecular mass22917.3 Da
Isoelectric point6.27
Protein length209 amino acids
Structural information
PFAMPF00440
Orthologs
M. tuberculosis H37RvRv0238
M. lepromatosis Mx1-22AMLPM_2568
Cross-references
UniProtQ7APU1
Gene OntologySequence-specific dna binding transcription factor activity, Regulation of transcription, dna-dependent
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY)
CommentsML2568c, len: 208 aa. Possible transcriptional regulatory protein (TetR-family). Similar to several putative transcriptional regulators e.g. Mycobacterium tuberculosis Rv0238 TR:O53661 (EMBL:AL021929) fasta scores: E(): 0, 80.9% id in 199 aa, and to Streptomyces coelicolor TR:CAB77290 (EMBL:AL160312) fasta scores: E(): 2.7e-20, 39.0% identity in 205 aa. Contains Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family.
Functional categoryRegulatory proteins
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS30632703063896-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2568c|ML2568c
MAGGAKRIPRAVREQQMLDAAVQMFSVNGYHKTSMDAIAAEAQISKPMLYLYYGSKEDLFGACLNREMSRFIAMVRADIDFTQSPKDLLRNTIVSFLRYIDANRASWIVMYIQAMSLPAFAQTVREARDQITELVAGLMRVGTRSSRPDHEYEIMAGALVGAGEAMATRLTTGDIAVDEAAELMINLFWHGLKGAPADRDFGPSIVAG
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