Gene ML2588 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameyrbE1B
Gene length870 bp
IdentifierML2588
Location 3091581 bp
Protein summary information
Molecular mass30256.4 Da
Isoelectric point8.9
Protein length290 amino acids
Structural information
PFAMPF02405
Orthologs
M. tuberculosis H37RvRv0168
M. lepromatosis Mx1-22AMLPM_2588
Cross-references
UniProtQ9CD15
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductCONSERVED HYPOTHETICAL INTEGRAL MEMBRANE PROTEIN YRBE1B
CommentsML2588, len: 289 aa. Probable yrbE1B, conserved hypothetical integral membrane protein. Highly similar to several Mycobacterium tuberculosis hypothetical proteins found within the four Mce loci, associated with virulence, e.g. Rv0168 TR:O07413 (EMBL:Z97050) fasta scores: E(): 0, 85.1% identity in 289 aa. Orthologue of M. tuberculosis YrbE1B (Rv0168). Contains possible membrane spanning hydrophobic domains.
Functional categoryVirulence, detoxification, adaptation
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS30915813092450+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2588|yrbE1B
MSTAAVLRARFPRAAANLNRYGGAAARGIDDIGQMSWFGLIALGNIPNALSRYRKETLRLIAQIGMGTGAMAVVGGTAAIVGFVTLSGSSLVAIQGFASLGAIGVEAFTGFFAALINVRIAAPVITGIVMAATVGAGATAELGAMRISEEIDALEVMSIKSISFLVTTRILAGLVVIVPLYAVAMIMAFLSPHIITTVLYGQSNGTYEHYFRTFLRPDDVFWSFLEAVIITAVVMITHCYYGYTANGGPVGVGEAVGRSMRFSLVSVQVVVLSATLALYGVDPNFALTV
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