Gene ML2590 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namemce1B
Gene length1041 bp
IdentifierML2590
Location 3093776 bp
Protein summary information
Molecular mass37697.2 Da
Isoelectric point9.0
Protein length347 amino acids
Structural information
PFAMPF02470
Orthologs
M. tuberculosis H37RvRv0170
M. lepromatosis Mx1-22AMLPM_2590
Cross-references
UniProtQ9CD13
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductMCE-FAMILY PROTEIN MCE1B
CommentsML2590, len: 346 aa. mce1B, Mce-family protein. Highly similar to several Mycobacterium tuberculosis hypothetical proteins found within the four Mce loci, associated with virulence, e.g. Rv0170 TR:O07414 (EMBL:Z97050) fasta scores: E(): 0, 75.1% identity in 346 aa. Orthologue of M. tuberculosis mce1B (Rv0170). Contains a possible N-terminal signal sequence.
Functional categoryVirulence, detoxification, adaptation
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS30937763094816+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML2590|mce1B
MKLTGTVVRLSIFSLVLLLFTVMIIVVFGQMRFGRTNGYTAEFTNISGLRTGQFVRASGVEVGKVNSVALINGGTRVRVKFNVDRSVPLYQSTTAQIRYLDLIGNRYLELKHGEGQGSEKIMPAGGLIPLSRTSPALDLDALIGGFKPLFRALDPDKINTIASAIVAAFQGQGGTINDILDQTAQLTTAIGERDQAIGEVVKNLNVVLDTTVRHRKEFDQTVNNLEILITGLKDHGDQLAGSFAHISNAAGTVANLLAEDHALLHKSINYLDGIQQPLIDQRLQLEDYLHKLPTVLNQIGRTIGSYGDFVNFYSCDITLKINGLQPGGPVRTVRLFQQPTGRCTPQ
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