Gene ML2635c
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE NAD(P) TRANSHYDROGENASE (SUBUNIT ALPHA) PNTAB [SECOND PART; INTEGRAL MEMBRANE PROTEIN] (PYRIDINE NUCLEOTIDE TRANSHYDROGENASE SUBUNIT ALPHA) (NICOTINAMIDE NUCLEOTIDE TRANSHYDROGENASE SUBUNIT ALPHA) |
| Comments | ML2635c, len: 112 aa. Probable pntAB, pyridine transhydrogenase subunit [alpha]2 (EC 1.6.1.2). Similar to Mycobacterium tuberculosis PntAB OR Rv0156 TR:P96833 (EMBL:Z92770) fasta scores: E(): 3.5e-30, 83.0% identity in 100 aa, and to Rhodospirillum rubrum nicotinamide nucleotide transhydrogenase, subunit alpha 2 PntAB TR:Q59764 (EMBL:U01158) fasta scores: E(): 6.1e-11, 42.7% identity in 89 aa. Note this is the equivalent to the very C-terminal hydrophobic domain of the larger E. coli and bovine mitochondrial enzymes. Contains possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF01262 AlaDh_PNT, Alanine dehydrogenase/pyridine nucleotide transhydrogenase. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3152888 | 3153226 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML2635c|pntAb
MYDELLANLAILVLSGFVGFAVISKVPNTLHTPLMSGTNAIHGIVLLGALVVFGEVAQPSLAVQIILFVAVVFGTLNVIGGFIVTDRMLGMFRGKKKASAVKTEKAAESVAK
Bibliography
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