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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE SERINE PROTEASE PEPA (SERINE PROTEINASE) (MTB32A)
CommentsML2659c, len: 354 aa. Probable pepA, secreted serine protease (EC 3.4.21.-). Similar to many including: Mycobacterium paratuberculosis serine protease Rv0125 TR:Q50320 (EMBL:Z23092) fasta scores: E(): 0, 71.4% in 364 aa, Mycobacterium tuberculosis hypothetical 34.9 kda protein TR:O07175 (EMBL:Z96071) fasta scores: E(): 0, 70.1% in 358 aa, and to Escherichia coli protease DegS precursor SW:DEGS_ECOLI (P31137) fasta scores: E(): 2.1e-16, 32.0% in 356 aa. Contains a possible N-terminal signal sequence. Contains Pfam match to entry PF00089 trypsin, Trypsin. Contains Pfam match to entry PF00595 PDZ, PDZ domain (Also known as DHR or GLGF).
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS31820833183147-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML2659c|pepA
MSRQPHRSLWRSWLVSTLAALGLSLAVVPGSATPSGPSTLALDRFSNRPPLPLNPAAMVAPQVVNISTRLGYNSAVGAGTGIVIDSSGVVLTNNHVISGATDISAFDVGNGKTYGVDVVGYDRTQDVAVLQLRGASNLPTAVIGGDVAIGEPIVALGNTGGQGGLPSVLPGRVVALNQTVQASEPLTGAQETLSGLIQVDAPIKPGDSGGPVVNSRGQVVGMNTAATDNYKMLGGQGFAIPIGQAMEVVGAIRSGAGSNTVHIGPTAFFGLGVLDNNGNGARVARVVATGPAAMAGISVGDIITSVDGVPISEATAMTNVLVPHHPGETVAVNYRSAGGGDLTANVTLAEGPPA
      
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