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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductOXIDATIVE STRESS RESPONSE REGULATORY PROTEIN OXYS
CommentsML2663c, len: 310 aa. oxyS, oxidative stress response regulatory protein. Similar to Mycobacterium tuberculosis OxyS|Rv0117 protein TR:O33175 (EMBL:AJ000188) fasta scores: E(): 0, 81.5% in 314 aa, and to Streptomyces coelicolor A3 OxyR a regulator of the hydroperoxide reductase system TR:Q9RN71 (EMBL:AF186371) fasta scores: E(): 5.9e-16, 31.2% in 292 aa. Contains a putative helix-turn-helix motif situated between residues 16..37 (+4.35 SD). Contains a probable helix-turn-helix motif at aa 16-37 (Score 1517, SD +4.35) Contains Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family. Contains PS00044 Bacterial regulatory proteins.
Functional categoryRegulatory proteins
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS31893843190316-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML2663c|oxyS
VLFRQLEYFVAVAQERHFARAAERCYVSQPALSSAIAKLERELNVTLINRGHSFEGLTPEGERLVVWAKRILAEHDAFKAEVHAVRSGITGTLRLGTVPTASTTASLVLSAFCSEHPLIKVQICSRLPVTELHRRLGDFELDAVIVHSAPDDTHAVDLVPLYHEHYVLVSPADMLPPGASVLAWPEASQLPLALLTPDMRDRQLIDRAFAGHAITATPQVETDSVASLFAQVATGNWACIVPHTWLWTTPIGAEIRAVEMVDPVLKADVALATNSAGPGSPVARALVASAKQLALNEFFEAQLAGITRRR
      
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