Gene MMAR_1248 in Mycobacterium marinum M
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namesigF
Gene length789 bp
IdentifierMMAR_1248
Location 1519716 bp
Protein summary information
Molecular mass29192.8 Da
Isoelectric point5.16
Protein length263 amino acids
Structural information
PFAMB2HDZ0
Orthologs
M. tuberculosis H37RvRv3286c
Cross-references
UniProtB2HDZ0
Gene OntologyRegulation of transcription, dna-dependent, Sigma factor activity, Sequence-specific dna binding transcription factor activity, Dna-dependent transcription, initiation
Precomputed results
BLASTReport
General annotation
TypeCDS
Functionthe sigma factor is an initiation factor that promotes attachment of the RNA polymerase to specific initiation sites and then is released. thought to be involved in survival and proliferation in lung granulomas during infection. thought to be involved in virulence and persistence processes. modulates expression of the 16 kDa alpha-crystallin homologue. negatively regulated by RsbW/UsfX.
Productalternate RNA polymerase sigma factor SigF
Comments-
Functional categoryInformation pathways
Coordinates
TypeStartEndOrientation
CDS15197161520504+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium marinum M|MMAR_1248|sigF
VTSRTAGGSSSRPNEYADVPEMFRELATFDADSPNFQRHRDTIVERCLPLADHIARRFEGRGEPRDDLVQVARVGLVNAVVRFDVETGSDFVSFAVPTIMGEVRRHFRDNSWSVKVPRRLKELHLRLGAATAELSQRLGRAPTATELAAELEMDRAEVVEGLVAGSSYNTLSIDSGSGSEDDDARAIADTLGDMDAGLDRIEDRESLRPLLEALPERERTVLVLRFFDSMTQTQIAERVGISQMHVSRLLAKSLARLRDQLE
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