Gene MMAR_1694 in Mycobacterium marinum M
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameligA
Gene length2064 bp
IdentifierMMAR_1694
Location 2041858 bp
Protein summary information
Molecular mass75053.7 Da
Isoelectric point5.27
Protein length688 amino acids
Structural information
PFAMB2HIF0
Orthologs
M. tuberculosis H37RvRv3014c
Cross-references
UniProtB2HIF0
Gene OntologyDna binding, Dna ligase (nad+) activity, Dna repair, Dna replication, Intracellular, Magnesium ion binding, Manganese ion binding, Zinc ion binding
Enzyme Classification6.5.1.2
Precomputed results
BLASTReport
General annotation
TypeCDS
Functionthis protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. it is essential for DNA replication and repair of damaged DNA [catalytic activity: NAD(+) + (deoxyribonucleotide)(N) + (deoxyribonucleotide)(M) = AMP + nicotinamide nucleotide + (deoxyribonucleotide)(N+M)].
ProductDNA ligase [NAD dependent] LigA
Comments-
Functional categoryInformation pathways
Coordinates
TypeStartEndOrientation
CDS20418582043921+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium marinum M|MMAR_1694|ligA
MTPEVLRQWQELAEQVREHQFRYYVRDAPVITDAEFDELLRRLEALEEQYPELRTPDSPTQLVGGAGFATEFEPVEHLERMLSLDNAFNTEELTAWAGRIHADVGDSAAYLCELKIDGVALSLVYEGGRLTRASTRGDGRTGEDVTLNARTIEDVPERLSHSEDHRMPEVLEVRGEVFFRVADFQALNASLVEEGKAPFANPRNSAAGSLRQKDPAVTARRRLRMICHGLGHTEGFRPATLHQAYLALQAWGLPVSQHTTLVADLAGVQERIDYWGEHRHEVDHEIDGVVVKVDDVALQRRLGSTSRAPRWAIAYKYPPEEAQTKLLDIRVNVGRTGRVTPFAFMTPVKVAGSTVAQATLHNASEVKRKGVLIGDTVVIRKAGDVIPEVLGPVVDLRDGSEREFVMPTTCPECGTPLAPEKEGDADIRCPNTRSCPGQLRERVFHVSSRNALDIEMLGYEAGAALLSARVIGDEGDLFGLTEEELLRTDLFRTKAGDLSANGRRLLANLDKAKAAPLWRVLVALSIRHVGPTAARALATEFGSIDAIVSATTEQLAAVEGVGPTIASAVSEWFTVDWHREIVEKWRAAGVRMADERDDSVPRTLAGVTVVVTGSLPGFSRDEAKEAIVTRGGKAAGSVSKKTSYVVAGDAPGSKYDKAVELGVPILDEDGFRKLLEQGPPAEVGEPT
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