Gene MMAR_1769 in Mycobacterium marinum M
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namedrrC
Gene length822 bp
IdentifierMMAR_1769
Location 2141334 bp
Protein summary information
Molecular mass29801.7 Da
Isoelectric point8.99
Protein length274 amino acids
Structural information
PFAMB2HIM4
Orthologues
M. tuberculosisRv2938
Cross-references
UniProtB2HIM4
Gene OntologyAtp binding, Atpase activity, coupled to transmembrane movement of substances, Membrane, Transport
Precomputed results
BLASTReport
General annotation
TypeCDS
Functionprobably involved in active transport of phthiocerol dimycocerosate (dim) across the membrane (export). DrrA, DrrB and DrrC may act jointly to confer daunorubicin and doxorubicin resistance by an export mechanism. probably responsible for the translocation of the substrate across the membrane and localization of dim into the cell wall.
Productdaunorubicin-DIM-transport integral membrane protein ABC transporter DrrC
Comments-
Functional categoryCell wall and cell processes
Coordinates
TypeStartEndOrientation
CDS21413342142155-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium marinum M|MMAR_1769|drrC
MTSQEIAFAPAQSQHTDHSARLLIWQTLVQTQRILTRWSRDFVTLIEALVFPILFMLVLKIVLGNLIYAVTHHDAMYSIVPLIALGAAITGSAFVAIDLMRERTSGLLSRLWVLPVHRMSGLMARILADAVRILFTTLVMLGVGILMGFEFRQGLIASLMWLCVPVTLGIAFAVMVTTVALYSSQAVIVEGVELTQAIAIFFSTGLIPLDQYPHWIQPVVAHQPVSYAVSAMRGLSMGGPVLLPMIGVLLWTAGICAVCAVPLAVGWRRASTH
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