Gene MMAR_1771 in Mycobacterium marinum M
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namedrrA
Gene length996 bp
IdentifierMMAR_1771
Location 2143027 bp
Protein summary information
Molecular mass35728.8 Da
Isoelectric point5.71
Protein length332 amino acids
Structural information
PFAMB2HIM6
Orthologues
M. tuberculosisRv2936
Cross-references
UniProtB2HIM6
Gene OntologyAtp binding, Atpase activity
Precomputed results
BLASTReport
General annotation
TypeCDS
Functionprobably involved in active transport of antibiotic and phthiocerol dimycocerosate (dim) across the membrane (export). DrrA, DrrB and DrrC may act jointly to confer daunorubicin and doxorubicin resistance by an export mechanism. responsible for energy coupling to the transport system.
Productdaunorubicin-DIM-transport ATP-binding protein ABC transporter DrrA
Comments-
Functional categoryCell wall and cell processes
Coordinates
TypeStartEndOrientation
CDS21430272144022-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium marinum M|MMAR_1771|drrA
MRNNDLAVEVRGVRKAFGDVVALNDISFEVGRGEVIGLLGPNGAGKTTMVDILSTLTRPDAGSAHVAGSDVVAQPAGVRRSIMVTGQQVAVDDGLTGEQNLVLFGRLYGLRKSRARQRAQELLDQFGLTYAGKRLVRTYSGGMRRRIDIACGLVVEPQVAFLDEPTTGLDPRSRQAIWDLVTSFKKLGIATLLTTQYLEEADALSDRIILIDHGKIIADGTANELKHRAGDTFCEIVPRHLKDLDATVAALGSLLPEHNRAMVTSESDRITMPAPDGTRTLIEAARRIDEANIELADIALRRPSLDDVFLSMTTDPSEAHALSHVASGAML
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