Gene MMAR_2017 in Mycobacterium marinum M
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namedut
Gene length465 bp
IdentifierMMAR_2017
Location 2435230 bp
Protein summary information
Molecular mass15760.9 Da
Isoelectric point5.45
Protein length155 amino acids
Structural information
PFAMB2HM03
Orthologues
M. tuberculosisRv2697c
Cross-references
UniProtB2HM03
Gene OntologyDutp diphosphatase activity, Dutp metabolic process, Magnesium ion binding
Enzyme Classification3.6.1.23
Precomputed results
BLASTReport
General annotation
TypeCDS
Functioninvolved in biosynthesis of thymidylate. this enzyme is involved in nucleotide metabolism: it produces dump, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA [catalytic activity: dUTP + H(2)O = dump + pyrophosphate].
Productdeoxyuridine 5'-triphosphate nucleotidohydrolase DutT
Comments-
Functional categoryIntermediary metabolism and respiration
Coordinates
TypeStartEndOrientation
CDS24352302435694+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium marinum M|MMAR_2017|dut
VSNSLAVVRLDPGLPLPSRAHDGDAGVDLYSAEDVVLPPGQRALVRTGVAVAIPFGMVGLVHPRSGLASRVGLSIVNSPGTIDAGYRGELKVALINLDPATPIVVNRGDRIAQLLVQRVELLELVEVSSFDEAGLAATSRGDGGHGSSGGHASL
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