Gene MMAR_2045 in Mycobacterium marinum M
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameribD
Gene length783 bp
IdentifierMMAR_2045
Location 2466738 bp
Protein summary information
Molecular mass27664.4 Da
Isoelectric point5.47
Protein length261 amino acids
Structural information
PFAMB2HM30
Orthologs
M. tuberculosis H37RvRv2671
Cross-references
UniProtB2HM30
Gene Ontology5-amino-6-(5-phosphoribosylamino)uracil reductase activity, Riboflavin biosynthetic process
Precomputed results
BLASTReport
General annotation
TypeCDS
Functioninvolved in riboflavin biosynthesis (at the second and third steps). converts 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1H,3H)-pyrimidinedione 5'-phosphate [catalytic activity 1: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine + H(2)O = 5-amino-6-(5-phosphoribosylamino)uracil + NH(3)] [catalytic activity 2: 5-amino-6-(5-phosphoribitylamino)uracil + NADP(+) = 5-amino-6-(5-phosphoribosylamino)uracil + NADPH].
Productbifunctional enzyme riboflavin biosynthesis protein RibD
Comments-
Functional categoryInformation pathways
Coordinates
TypeStartEndOrientation
CDS24667382467520-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium marinum M|MMAR_2045|ribD
MPDPTSGRSADAQLTLLGTDRQLTDEDLPEFYGYPAKLSGTWLRANFITSLDGGATVGGTSGGLAGPGDRAVFVLLRELADVILVGAGTVRIEGYSGAQLGVAERQQRQARGQSEVPQLAIATNSGQLDRDLPVFTRTEVPPLVLTAAAAVYDTRRRLTGLAEVVDCSGKDPHRVDEGLLLARLAGRGMRRILTEGGPTLFGSLIEQDLLDELCLTIAPVVVGGLPRRIASGPGQLQTRMHCAHVITDDAGYLYTRYVRA
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