Gene MMAR_2215 in Mycobacterium marinum M
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namefmt
Gene length939 bp
IdentifierMMAR_2215
Location 2664238 bp
Protein summary information
Molecular mass32660.6 Da
Isoelectric point7.83
Protein length313 amino acids
Structural information
PFAMB2HP60
Orthologs
M. tuberculosis H37RvRv1406
Cross-references
UniProtB2HP60
Gene OntologyMethionyl-trna formyltransferase activity, Translation
Enzyme Classification2.1.2.9
Precomputed results
BLASTReport
General annotation
TypeCDS
Functionmodify the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). the formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EftU-GTP. [catalytic activity : 10-formyltetrahydrofolate + L-methionyl-tRNA + H(2)O = tetrahydrofolate + N-formylmethionyl-tRNA]
Productmethionyl-tRNA formyltransferase Fmt
Comments-
Functional categoryInformation pathways
Coordinates
TypeStartEndOrientation
CDS26642382665176+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium marinum M|MMAR_2215|fmt
VRLVFAGTPETALPALHQLIDSPRHDVIAVLTRPDAASGRRGKPEPSPVARAALERDIPVLRPSRPNSAEFVAELSELAPQCCAVVAYGALLGDALLGVPPQGWVNLHFSLLPAWRGAAPVQAAIAAGDAVTGATTFQIEPSLDSGPVYGVVTETIRPTDTAGDLLGRLAVSGAELLSATLDGIAEGALTARPQPADGVTLAPKISVEQARVRWELPAPIIERRIRAVTPNPGAWTLIGDLRVKLGPVYLDAAVKPPGPLPPGAIQVDRKHVWVGTGSEPLRLGQVQPPGKKLMNAADWARGARLDPSVRAS
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