Gene MMAR_2387 in Mycobacterium marinum M
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namebioB
Gene length1050 bp
IdentifierMMAR_2387
Location 2882538 bp
Protein summary information
Molecular mass37598.9 Da
Isoelectric point4.68
Protein length350 amino acids
Structural information
PFAMB2HQ93
Orthologs
M. tuberculosis H37RvRv1589
Cross-references
UniProtB2HQ93
Gene Ontology2 iron, 2 sulfur cluster binding, 4 iron, 4 sulfur cluster binding, Biotin biosynthetic process, Biotin synthase activity, Iron ion binding
Enzyme Classification2.8.1.6
Precomputed results
BLASTReport
General annotation
TypeCDS
Functioninvolved in biotin synthesis. biotin synthase with flavodoxin, s-adenosylmethionine, and possibly cysteine to catalyze the last step of the biotin biosynthetic pathway. the reaction consists of the introduction of a sulphur atom into dethiobiotin, thus requiring activation of C-H bonds. biotin (vitamin H) is a prosthetic group in enzymes catalysing carboxylation and transcarboxylation reactions.
Productbiotin synthase BioB
Comments-
Functional categoryIntermediary metabolism and respiration
Coordinates
TypeStartEndOrientation
CDS28825382883587+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium marinum M|MMAR_2387|bioB
VTQAATRPSNDAGQDGVTEPDILAVARQQVLERGEGLNQEQVLQVLQLSEDRLEELLALAHDVRMRWCGPEVEVEGIISLKTGGCPEDCHFCSQSGLFSSPVRSAWLDIPSLVEAAKQTAKSGATEFCIVAAVRGPDARLLSQVAAGIEAIRNEVEINVACSLGMLTAEQVEQLAAMGVHRYNHNLETARSYFTNVVTTHTWEERWQTLTMVRDAGMEVCCGGILGMGETLEQRAEFAANLAELDPDEVPLNFLNPRPGTPFGDLEVLPAGEALKAVGAFRLALPRTMLRFAGGREITLGDLGAKRGILGGINAVIVGNYLTTLGRPAEADLELLEDLQMPLKALNASL
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