Gene MMAR_3698 in Mycobacterium marinum M
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namembtA
Gene length1653 bp
IdentifierMMAR_3698
Location 4555360 bp
Protein summary information
Molecular mass58436.8 Da
Isoelectric point5.42
Protein length551 amino acids
Structural information
PFAMB2HM94
Orthologs
M. tuberculosis H37RvRv2384
Cross-references
UniProtB2HM94
Gene OntologyLigase activity, Metabolic process
Precomputed results
BLASTReport
General annotation
TypeCDS
Functioninvolved in the biogenesis of the hydroxyphenyloxazoline-containing siderophore mycobactins (initiation step of mycobactin chain growth). activates the mycobactin ACP in two half-reactions: activates salicylic acid as acyladenylate (adenylation step) + transfers activated salicylate to the MbtA ACP as a thioester (arylation step).
Productbifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase
Comments-
Functional categoryCell wall and cell processes
Coordinates
TypeStartEndOrientation
CDS45553604557012+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium marinum M|MMAR_3698|mbtA
VPVTSAQPPRPGPVAGFIPYPPERVASYRAAGYWTGRSIGSLLRQAAARWPDRVGVVDAGASHTFCELDKLADRAAAGFVSLGIAPGDRVLLQLPNSCRFAVALFGLLRAGAIPVMCLPGHRLAELHHFAEVSGAVGLIVAQHAGGFDYRSMAERLVAAHPQLRHVIIDGESGPFLPWSSLSEGATPDIDVDTTSPALLLVSGGTTGTPKLIPRTHDDYVYNATASAQLCRLTADDVYLVSLPAAHNFPLACPGILGSMAVGATIVFSTDPSPEAAFTLIERHGVTVTALVPALAKLWTQACDWEPVTPKSLRLLQVGGSRLEPEDARQAREALTPGLQQVFGMAEGLLNFTRLEDPPDLLEHTQGRPLCSADELRIVDGAGAPVAPGAEGELLVRGPYTINGYFCADRDNERCFDPAGFYRSGDLVRLRDDGYLQVTGRVKDVICRCGETISAQDLEEQLLSHPAIRSAAAVPLPDPDMGELICAAIVFAGPPQTPQTLSGLNDYLEQRGVAAHIRIDRLVAMPSLPTTPVGKIDKKAIASQILTTTAT
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