Gene MMAR_3844 in Mycobacterium marinum M
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namepdhA
Gene length1092 bp
IdentifierMMAR_3844
Location 4780193 bp
Protein summary information
Molecular mass39780.8 Da
Isoelectric point5.22
Protein length364 amino acids
Structural information
PFAMB2HNK2
Orthologs
M. tuberculosis H37RvRv2497c
Cross-references
UniProtB2HNK2
Gene OntologyGlycolysis, Oxidation-reduction process, Pyruvate dehydrogenase (acetyl-transferring) activity, Thiamine pyrophosphate binding
Precomputed results
BLASTReport
General annotation
TypeCDS
Functioninvolved in energy metabolism. the pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA & CO(2). it contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) & lipoamide dehydrogenase (E3) [catalytic activity: acetyl-CoA + dihydrolipoamide = CoA + s-acetyldihydrolipoamide].
Productpyruvate dehydrogenase E1 component (alpha subunit) PdhA
Comments-
Functional categoryIntermediary metabolism and respiration
Coordinates
TypeStartEndOrientation
CDS47801934781284-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium marinum M|MMAR_3844|pdhA
MADRPRIPMTVGLEPVQLVNADGEPTDEHRYSRDLPEETLCWLYEMMVVTRELDAEFINLKRQGELALFASCRGQEAAQVGATACLRKTDWLFPQYRELGAYLVRGIPPGHVGAAWRGTWHGGLEFTKKCCAPISVPIGTQALHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDVHEALNFAAVFDAGCVFYVQNNQWAISVPVSKQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVTAEAAARARRGDGPTLIEAVTYRVGAHTTADDPGRYRSQEEVDHWLALDPISRYRSYLQGQGLWSQRLEERVAARSGRLRAELREAVFGASDFDVDDVFTTVFAEITPGLQTQRQQLRAELDRID
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