Gene MMAR_4355
in Mycobacterium marinum M
General annotation
| Type | CDS |
| Function | converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (by similarity).[catalytic activity] isopentenyl diphosphate + NAD(P)(+) + H(2)O = (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H. [cofactor] binds 1 3Fe-4S cluster (by similarity).[pathway] isoprenoid biosynthesis; dimethylallyl-PP biosynthesis; dimethylallyl-PP from 1-hydroxy-2-methyl-2-butenyl 4-diphosphate: single step [final step].[pathway] isoprenoid biosynthesis; isopentenyl-PP biosynthesis via DXP pathway; isopentenyl-PP from 1-deoxy-D-xylulose 5-phosphate:step 6 [final step]. |
| Product | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase IspH |
| Comments | - |
| Functional category | Lipid metabolism |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 5361720 | 5362718 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium marinum M|MMAR_4355|ispH
MVPTIDMGIPGASSSVAHVPTRRRVLLAEPRGYCAGVDRAVETVERALEKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEETDQVPEGAIVVFSAHGVAPTVYAAAAERNLQTIDATCPLVTKVHNEARRFARNDYDILLIGHEGHEEVVGTAGEAPEHVQLVDGLDGAERVTIRDEEKVVWLSQTTLSVDETMEIVARLRQRFPKLQDPPSDDICYATQNRQVAVKAMAPECDLVLVVGSRNSSNSVRLVEVALGAGAQAAYLVDWADDIDQSWLQGVTTVGVTSGASVPEVLVRGVLERLAESGYDMVQPVTTANETLVFALPREIRPAR
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