Gene MMAR_4387 in Mycobacterium marinum M
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namegreA
Gene length495 bp
IdentifierMMAR_4387
Location 5395065 bp
Protein summary information
Molecular mass18013.8 Da
Isoelectric point4.82
Protein length165 amino acids
Structural information
PFAMB2HT73
Orthologs
M. tuberculosis H37RvRv1080c
Cross-references
UniProtB2HT73
Gene OntologyDna binding, Regulation of transcription, dna-dependent, GO:0006350, Transcription elongation regulator activity, Translation elongation factor activity
Precomputed results
BLASTReport
General annotation
TypeCDS
Functionnecessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. the arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. cleavage of the nascent trancript by cleavage factors such as GreA or Greb allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
Producttranscription elongation factor GreA
Comments-
Functional categoryInformation pathways
Coordinates
TypeStartEndOrientation
CDS53950655395559+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium marinum M|MMAR_4387|greA
MTDTQVTWLTQESHDRLKAELDHLIANRPIIAAEINDRREEGDLRENGGYHAAREEQGQQEARIRQLQDLLNNAKVGEAPKQSGIALPGSVVKVYYNGDQSDSETFLIATRQEGVNDGKLEVYSPNSPLGGALIDAKVGETRSYTVPNGSVIEVTLISAEPYHS
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