Gene MMAR_4477 in Mycobacterium marinum M
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameispE
Gene length924 bp
IdentifierMMAR_4477
Location 5499211 bp
Protein summary information
Molecular mass31700.2 Da
Isoelectric point5.47
Protein length308 amino acids
Structural information
PFAMB2HDJ9
Orthologues
M. tuberculosisRv1011
Cross-references
UniProtB2HDJ9
Gene Ontology4-(cytidine 5'-diphospho)-2-c-methyl-d-erythritol kinase activity, Atp binding, Phosphorylation, Terpenoid biosynthetic process
Enzyme Classification2.7.1.148
Precomputed results
BLASTReport
General annotation
TypeCDS
Functionthought to be involved in deoxyxylulose-5-phosphate pathway (DXP) of isoprenoid biosynthesis (at the fourth step). catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol [catalytic activity: ATP + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol = ADP + 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol].
Product4-diphosphocytidyl-2-C-methyl-D-erythritol kinase IspE
Comments-
Functional categoryIntermediary metabolism and respiration
Coordinates
TypeStartEndOrientation
CDS54992115500134-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium marinum M|MMAR_4477|ispE
VPTGSATVRVPGKVNLYLAVGDRRDDGYHELTTVFHAVSLVDEVTVRNADLLSLEVVGEGADRLPTDKRNLAWQAAELMAEHVGRAPDVSIFIDKSIPVAGGMAGGSADAAAVLVAMNSLWELNLPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFARSGLSTPAVFTELDRLRDVGSPPRLAEPGPVLAALAAGDPEQLAPLLGNEMQAAAVSLDPALRRALRAGVEAGALAGIVSGSGPTCAFLCRTAESALDVSAQLSGAGVCRTVRIATGPVPGARVVPTPGIAE
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