Gene MTB000019
in Mycobacterium tuberculosis H37Rv
General annotation
| Type | rRNA |
| Function | - |
| Product | Ribosomal RNA 16S |
| Comments | rrs, 16s rRNA gene (alternate gene name: rrnS). |
| Functional category | Stable rnas |
| Mutant | Essential gene for in vitro growth of H37Rv in a MtbYM rich medium, by Himar1 transposon mutagenesis (see Minato et al. 2019). Different mutations in rrs are associated with different patterns of resistance or susceptibility to capreomycin, kanamycin, amikacin, and viomycin (See Alangaden et al., 1998; Maus et al., 2005a; Maus et al., 2005b). Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| rRNA | 1471846 | 1473382 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Bibliography
- Alangaden GJ et al. [1998]. Mechanism of resistance to amikacin and kanamycin in Mycobacterium tuberculosis. Mutant
- Maus CE et al. [2005]. Mutation of tlyA confers capreomycin resistance in Mycobacterium tuberculosis. Mutant
- Maus CE et al. [2005]. Molecular analysis of cross-resistance to capreomycin, kanamycin, amikacin, and viomycin in Mycobacterium tuberculosis. Mutant
- Minato Y et al. [2019]. Genomewide Assessment of Mycobacterium tuberculosis Conditionally Essential Metabolic Pathways. Mutant
