Gene Mb0002
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | DNA POLYMERASE III (BETA CHAIN) DNAN (DNA NUCLEOTIDYLTRANSFERASE) |
| Comments | Mb0002, dnaN, len: 402 aa. Equivalent to Rv0002,len: 402 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 402 aa overlap). dnaN, DNA polymerase III (beta chain) (EC 2.7.7.7) (see citations below),equivalent to other Mycobacterial DNA POLYMERASES III BETA CHAIN e.g. NP_301130.1|NC_002677 from Mycobacterium leprae (399 aa); Q9L7L6|DP3B_MYCPA from Mycobacterium avium subsp. paratuberculosis (399 aa); P52851|DP3B_MYCSM from Mycobacterium smegmatis (397 aa); etc. Also highly similar to others e.g. P27903|DP3B_STRCO DNA POLYMERASE III BETA CHAIN from Streptomyces coelicolor (376 aa), FASTA scores: opt: 1189, E(): 0, (52.8% identity in 337 aa overlap); P21174|DP3B_MICLU from Micrococcus luteus (310 aa); P52023|DP3B_SYNP7 from Synechococcus sp. strain PCC 7942 (375 aa); etc. Overlaps and extends CDS in neighbouring cosmid MTCY10H4.01. |
| Functional category | Information pathways |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2052 | 3260 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0002|dnaN
MDAATTRVGLTDLTFRLLRESFADAVSWVAKNLPARPAVPVLSGVLLTGSDNGLTISGFDYEVSAEAQVGAEIVSPGSVLVSGRLLSDITRALPNKPVGVHVEGNRVALTCGNARFSLPTMPVEDYPTLPTLPEETGLLPAELFAEAISQVAIAAGRDDTLPMLTGIRVEILGETVVLAATDRFRLAVRELKWSASSPDIEAAVLVPAKTLAEAAKAGIGGSDVRLSLGTGPGVGKDGLLGISGNGKRSTTRLLDAEFPKFRQLLPTEHTAVATMDVAELIEAIKLVALVADRGAQVRMEFADGSVRLSAGADDVGRAEEDLVVDYAGEPLTIAFNPTYLTDGLSSLRSERVSFGFTTAGKPALLRPVSGDDRPVAGLNGNGPFPAVSTDYVYLLMPVRLPG
Bibliography
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