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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN
CommentsMb0038c, -, len: 441 aa. Equivalent to Rv0037c,len: 441 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 441 aa overlap). Probable conserved integral membrane protein, member of major facilitator superfamily (MFS) possibly involved in transport of macrolide, showing some similarity to Rv1258c|MTCY50_24 (419 aa), FASTA score: (25.2% identity in 408 aa overlap); and to AL049826|SCH24_20 from Streptomyces coelicolor (425 aa), FASTA scores: opt: 725, E(): 0, (36.1% identity in 418 aa overlap). Also similarity with several MACROLIDE-EFFLUX PROTEINS e.g. from S. pyogenes (405 aa),FASTA scores: E(): 1.3e-06, (22.8% identity in 416 aa overlap).
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS3986141186-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0038c|Mb0038c
MPRVEVGLVIHSRMHARAPVDVWRSVRSLPDFWRLLQVRVASQFGDGLFQAGLAGALLFNPDRAADPMAIAGAFAVLFLPYSLLGPFAGALMDRWDRRWVLVGANTGRLALIAGVGTILAVGAGDVPLLVGALVANGLARFVASGLSAALPHVVPREQVVTMNSVAIASGAVSAFLGANFMLLPRWLLGSGDEGASAIVFLVAIPVSIALLWSLRFGPRVLGPDDTERAIHGSAVYAVVTGWLHGARTVVQLPTVAAGLSGLAAHRMVVGINSLLILLLVRHVTARAVGGLGTALLFFAATGLGAFLANVLTPTAIRRWGRYATANGALAAAATIQVAAAGLLVPVMVVCGFLLGVAGQVVKLCADSAMQMDVDDALRGHVFAVQDALFWVSYILSITVAAALIPEHGHAPVFVLFGSAIYLAGLVVHTIVGRRGQPVIGR
      
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